Immune Dysregulation

A Mouse Model for the Immune Dysregulation Subtype of Autism « Lisa Ackerman – Real Help Now.

I can’t really tell you how much I wish this were more well-known. I know that I can’t make anyone else really feel the same way, either. Not in the meaningful way I’d like, at least. I don’t think anyone can feel it properly unless they’ve been there.

The medical community might think it’s not worth exploring but try asking the mom that had a miscarriage two months before getting pregnant with her ASD son. The one whose miscarried pregnancy was completely not right in every way from the very start. The pregnancy that was likely miscarried for some sort of immune dysfunction.

The bad pregnancy that probably affected the pregnancy immediately following it two months later.

Whatever happened to my immune system happened to him. He was born with those immune problems and spent the first three years of his like always sick. Vaccines (especially the Hep B) played such a large role in keeping him sick and making him sicker. Each shot make him slip further away.

I find myself having many of the same issues but I’m older, I’m not developing and learning and becoming a person. I already know how to behave appropriately so when these issues arise in me, I already know how to handle them, or at least control them. I already know it’s not normal.

He was an infant with no prior knowledge. He was a brand new being and all these things were imprinting in his brain as being normal.

And now his immune system is shot and his viral titers are crazy. He will not likely ever be able to stop taking antivirals and antifungals. It’s just an unfortunate reality. His recovery is completely reliant upon them. Without them, his ASD symptoms return. It’s been proven over and over in him. Take antivirals and symptoms disappear. Remove antivirals and symptoms return. We’ve replicated this scenario every year.

I’m not sure how much more proof anyone could need. You don’t even have to believe that he has immune dysfunction. All you need to do is believe that antivirals clearly improve his ASD status. He goes from mostly recovered while on it to not at all recovered when off. We can do this over and over and over and over. There’s obviously some kind of correlation that should give any doctor pause.

And yet I can’t get many western medical professionals to “get it” and understand autism is more than a set of psychological symptoms. We’re fortunate that we’ve got a wonderful ped and a wonderful DAN doctor. But it took us a long time to find a doctor that looked at the results instead of towing the party line.

Medicine should be progressive. We should be open to learning, not pressured by organizations and companies with an agenda.

These are the types of studies we need more doctors to read. We need more doctors that will employ critical thinking skills instead of looking up the same tired answers in a medical book or rehashing the same biased information from what has been proven many times over to be biased journals.

Maternal (possibly even paternal) immune dysregulation should matter. Immune dysregulation as a subtype of ASD should matter.

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MMR II and Autism: Microcompetition the Missing Link?

MMR II and Autism: Microcompetition the Missing Link?.

Fascinating story. I hope there’s more to come on this front.

Brain cell creation may lead to Alzheimer’s and autism cures

Brain cell creation may lead to Alzheimer’s and autism cures | Science updates | NewJerseyNewsroom.com — Your State. Your News.

I’ve always found this kind of thing fascinating. While I’m not at all impressed with the never-ending quest for genes (c’mon, there have now been over 40 genes identified; how many genes do we need to identify before we wonder if it’s really genes?) This is the best we’ll get out of the whole gene theory–which just brings it all back to being triggered by the environment, I might add. Gasp! Whodathunk it?

Regeneration, on the other hand, that’s another ball of wax altogether and brings out my Whovian fangirl. This is what science is about. This is what medicine should be about. Real research that produces real results. These are the things that bring us closer to understanding at least the one thing we do know about autism – many of those with ASD have structurally different brains.

Get scientists studying the right things. Metabolism, immune system and brains. Get out of the genes because it’s a dead-end.

 

Children with autism and gastrointestinal symptoms have altered digestive genes

Children with autism and gastrointestinal symptoms have altered digestive genes.

Let’s say it again: Genes Don’t Cause Autism

July 07, 2010

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